Physicians Committee for Responsible Medicine (PCRM), "Vioxx Tragedy Spotlights Failure of Animal Research," pcrm.org, Mar.
In safety testing, a drug must be proven to be safe for human use : it must be non life-threatening and avoid the occurrence of adverse drug reactions (ADR). It has been shown that the use of Vioxx increases in humans by 5 times the incidence of heart attacks ; surprisingly, 9 out of 11 studies on mice and rats have found Vioxx to be safe on blood vessels and hearts, and 6 studies on 4 species showed that it was actually protective against heart attack and vascular diseases (PCRM, 2005). "Footnotes & Sources." newint.org, June 1, 2011, Humane Research Australia (HRA), "Medical Research," humaneresearch.org.au, Jan. 2006, Mihir Zaveri, Mariel Padilla, and Jaclyn Peiser, "E.P.A.
Preliminatory results have already been collected in specific cases, such as a test of efficiency for a drug against cystic fibrosis, or chemotherapy for pancreatic cancer (Willyard 2015). (1998) Incidence of adverse drug reactions in hospitalized patients. Who is the author? Retrieved from https://animal-testing.procon.org/additional-resources/footnotes-sources/, ProCon.org.
Now, we aren’t going to be directly using humans, but instead alternatives such as synthetic skin or lab grown human cells. Nor, can they talk ? Animal Friends is a non-profit, non-governmental organization, founded in 2001 with the aim to promote animal protection and animal rights as well as veganism, as ethical, ecological and healthy lifestyle. The failure of these drugs in humans could have been prevented by better alternative testing and could have saved countless lives, both in human and non human beings. Says It Will Drastically Reduce Animal Testing," nytimes.com, Sep. 10, 2019, Frontiers, "Algorithm for Large-scale Brain Simulations,” science daily.com, Mar. Due to the different physical components, our bodies react differently from animals.
(2002) Specious science : why experiments on animals harm humans.
Based on a study by the FDA, 92% of drugs that pass animal tests fail human clinical trials. This poster has been selected among the 3 best posters of the congress demonstrating the growing interest in the field of alternatives to animal experimentation. Models of kidneys, liver, heart, etc. In the EU, the Cosmetics directive (regulation 1223/2009), enforced since 2013, fixes a testing ban on finished products and ingredients, which has been delayed for tests that have currently no validated alternative, such as reproductive toxicology or repeated-dose toxicity. Mandatory National Service – Should the United States Have Mandatory National Service? Alternatives to Animal Testing in Research — Insights and Future Directions, viagra sans ordonnace pharmacie ville lyon, A Message from the Pro Anima Scientific Committee. Right now the top five abused animals from testing are guinea pigs, hamsters, rabbits, dogs and primates. Bentham J. pcrm.org. In efficiency testing, a drug must show its therapeutic properties against a specific pathological state at a determined dose (that, combined with safety testing, should heal and not harm the patient). Harper Collins, U.S.A. Willyard C. (2015) The boom in mini stomachs, brains, breasts, kidneys, and more. (AGD/Audience Motivation) I want everyone in this class to close your eyes. ], ProCon.org.
Many classical examples arise in pharmacology, such as penicillin that would not have stand many animal tests (very toxic at low doses in guinea pigs, and various levels of toxicity in mammals). Nowadays, scientists seem to agree that many animals have a form of consciousness and pathways of feeling pain very similar to human beings.
Lazarou J., Pomeranz B.H., Corey P.N. He suggests that, more than the ability to be conscious of their fate, the fact that animals can feel pain through experiments is in itself an argument to avoid using them.
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